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KMID : 0361120150290020049
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Korean Journal of Transplantation
2015 Volume.29 No. 2 p.49 ~ p.53
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Metabolomics Research in Kidney Transplanta
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Lee Yu-Ho
Lee Sang-Ho
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Abstract
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Acute and chronic immune injury, drug toxicity, and cardiovascular complications remain a critical challenge following kidney transplantation. Success from these hurdles is closely associated with the ability to monitor patients and responsively adjust their medication. Metabolic and biochemical profiling (metabolomics) may enable detection of early changes in cell signal transduction regulation and biochemistry with high sensitivity and specificity. However, metabolomics have not been studied extensively in the field of kidney transplantation. This review describes the basic principles of metabolomics, summarizes recent studies, and suggests future perspectives.
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KEYWORD
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Kidney transplantation, Metabolomics, Biological markers
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